Millions of patients affected. Billions in avoidable cost. And a detection system that's decades behind.
Every year, 4.1 million hospitalized patients in the U.S. develop acute kidney injury.
That's 1 in 8 hospitalized patients — making AKI one of the most common and dangerous complications in modern healthcare.
hospitalized patients per year experience hospital-acquired AKI
hospitalized patients develops acute kidney injury
of hospital-acquired AKI is largely unreimbursed by insurance
Without continuous monitoring, kidney stress develops silently across the hospital stay — with risk compounding each day detection is delayed.
The gap between when kidney injury begins and when creatinine rises represents a critical missed window for intervention.
Detects AKI only after ~50% of kidney function is lost. By this point, the window for effective intervention has narrowed dramatically.
Identifies subtle physiological shifts that precede creatinine elevation — enabling clinical teams to intervene hours to days earlier.
Patient admitted for surgery or acute condition. Standard labs are drawn — kidney function appears normal.
Subtle physiological changes begin due to stress or medications. No labs reflect this yet. No alarm is triggered.
Kidney function continues to decline. Creatinine levels haven't risen. Clinical team remains unaware of the injury.
Lab results finally show elevated creatinine. By now, significant damage has occurred. Options are limited.
Patient requires ICU transfer or dialysis. Recovery is prolonged. Costs multiply. This was preventable.
Each day that AKI goes undetected, the financial burden multiplies — for the patient and the health system.
RenalSignal is building the technology to detect AKI earlier — before creatinine rises, before damage accumulates.
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